By Michael Lohmuller, Nicole Cook, and Logan Pauley

The illicit synthetic drug networks that fuel the ongoing opioid epidemic in the United States continue to evolve and adapt to changing incentives and pressures, finding innovative ways to exploit technology and increased global interconnectivity. C4ADS investigated these drug supply chains, conducting extensive multilingual analysis of Chinese corporate entities, the clear web, and social media, in order to better understand the methods by which they operate.   

Washington, DC: C4ADS 2020, 45p.

By Lauren Greenwood and Kevin Fashola

The issue brief examines the evolution of China’s role in global illicit fentanyl trade. China placed all forms of fentanyl and its analogues on a regulatory schedule in 2019, but the U.S. Drug Enforcement Administration (DEA) assesses China remains the primary country of origin for illicit fentanyl and fentanyl-related substances trafficked in the United States. While Mexican drug cartels have always been a critical node for smuggling illicit fentanyl into the United States, this brief finds that the links between Chinese and Mexican actors in the fentanyl trade has grown in complexity, including the development of sophisticated money laundering operations. Finally, the brief concludes that while cooperation between the United States and China remains limited, there are opportunities for the United States to work with other countries on counter-narcotic enforcement.
 Washington, EC:  U.S.-China Economic and Security Review Commission,   

By Roderic Broadhurst, Matthew Ball and Harshit Trivedi

A snapshot of the sale of fentanyl and its analogues across several popular darknet markets between 2 January and 27 March 2019 reveals the amount, types and physical forms available. Of the 127,541 unique drug listings identified, 13,135 were opioids (10.3% of all drugs), of which 1,118 (0.876% of all drugs) were fentanyl or its analogues. Between 27.3 and 39.3 kilograms of fentanyl and its derivatives were available over the period. The average price of fentanyl was A$99 per gram, while carfentanil was A$26.8 per gram. The shipping methods, cross-market operations and product specialisation of the 303 active fentanyl vendors on these darknet markets are also described.

Canberra: Australian Institute of Criminology, 2020. 14p.

By United States and Rand Corporation

The Commission on Combating Synthetic Opioid Trafficking, established under Section 7221 of the National Defense Authorization Act for Fiscal Year 2020, was charged with examining aspects of the synthetic opioid threat to the United States—specifically, with developing a consensus on a strategic approach to combating the illegal flow of synthetic opioids into the United States. This final report describes items involving the illegal manufacturing and trafficking of synthetic opioids, as well as the deficiencies in countering their production and distribution, and includes action items directed to appropriate executive branch agencies and congressional committees and leadership. Get appendices to the report.

Rand, 2022. 148p.

By Bryce Pardo, Lois M. Davis, Melinda Moore

The opioid overdose crisis has continued to accelerate in recent years because of the arrival of potent synthetic opioids, such as fentanyl and related substances. Although several synthetic opioids have legitimate medical applications, the majority of overdoses are due to illicitly manufactured imports. Researchers from the Homeland Security Operational Analysis Center evaluated publicly available data to better understand the dimensions of the consumption and supply of these substances. They performed four tasks designed to gain insight into this new and quickly evolving phenomenon: (1) They evaluated trends in overdoses across regions and over time. Understanding where overdoses due to synthetic opioids occur provides a rough proxy for where law enforcement should prioritize screening efforts for packages that enter the country destined for such markets. (2) They evaluated the supply of fentanyl and related substances using public data from state and local forensic laboratories that report to national systems. The authors note a relationship between lab exhibits and fatal overdoses across regions and over time. (3) They examined the online markets for synthetic opioids. The team collected quantitative and qualitative data from online marketplaces and vendors to better understand what supply and concealment mechanisms vendors use when shipping product to the United States. (4) They evaluated the adulterants and other bulking agents used in retail distribution. There are limitations to each of these approaches, and the authors provide caveats to interpreting their findings.

Santa Monica, CA: Rand, 2019. 91p.

By Bryce Pardo and Peter Reuter

  The synthetic opioid crisis in North America has increased fatal overdose rates to unprecedented levels within a matter of a few years. It involves new technologies, a new source of supply (the chemical industry in China), and new forms of distribution (the internet and mail). These elements are perhaps even more difficult to suppress than other supply sources from foreign countries. This has led to an assumption that nothing can be learned from prior experience in trying to control drug markets. In this paper, we first explore what might be learned from some notable past successes. We begin by examining a set of episodes in which enforcement against a specific illegal drug market had more than a brief impact on supply, though the enforcement may have caused other harms. Examples include the near-elimination of the quaaludes market in the 1980s and the “heroin drought” in Australia in the early 2000s. Exploring common features of these past successes reveals insights that may reduce the risk of fatal overdose. We then examine the characteristics of fentanyl distribution in detail, noting that taken individually, the

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  differences (such as the low costs of fentanyl production and its distribution by mail) are in fact not so distinctive: it is the combination of many differences that creates the unique threat. In response, authorities need to change priorities in supply control domestically. Prior to the arrival of fentanyl and other synthetic opioids, it was reasonable for police and prosecutors to focus on (1) raising prices and restricting availability to reduce consumption and (2) minimizing the violence and disorder around street markets. Yet today, a more important goal may be to reduce the toxicity of the supply and thus the number of drug overdoses. This paper applies the insights of the “focused deterrence” approach developed by David Kennedy and Mark Kleiman, which involves using multiple levers to attain a specific policy goal. We conclude with some specific suggestions for local and national supply-control agencies— including the need to focus more on regulating rather than reducing markets to minimize harm, and to distinguish between markets not yet swamped by fentanyl or in transition and those where the drug is entrenched. Strategies appropriate in one context may not serve well in another.

Washington, DC: Brookings Institution, 2020. 21p.

By Julie O’Donnell, Lauren J. Tanz, R. Matt Gladden, Nicole L. Davis, Jessica Bitting

During May 2020–April 2021, the estimated number of drug overdose deaths in the United States exceeded 100,000 over a 12-month period for the first time, with 64.0% of deaths involving synthetic opioids other than methadone (mainly illicitly manufactured fentanyls [IMFs], which include both fentanyl and illicit fentanyl analogs).* Introduced primarily as adulterants in or replacements for white powder heroin east of the Mississippi River (1), IMFs are now widespread in white powder heroin markets, increasingly pressed into counterfeit pills resembling oxycodone, alprazolam, or other prescription drugs, and are expanding into new markets, including in the western United States† (2). This report describes trends in overdose deaths involving IMFs (IMF-involved deaths) during July 2019–December 2020 (29 states and the District of Columbia [DC]), and characteristics of IMF-involved deaths during 2020 (39 states and DC) using data from CDC’s State Unintentional Drug Overdose Reporting System (SUDORS).

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  During July 2019–December 2020, IMF-involved deaths increased sharply in midwestern (33.1%), southern (64.7%), and western (93.9%) jurisdictions participating in SUDORS. Approximately four in 10 IMF-involved deaths also involved a stimulant. Highlighting the need for timely overdose response, 56.1% of decedents had no pulse when first responders arrived. Injection drug use was the most frequently reported individual route of drug use (24.5%), but evidence of snorting, smoking, or ingestion, but not injection drug use was found among 27.1% of decedents. Adapting and expanding overdose prevention, harm reduction, and response efforts is urgently needed to address the high potency (3), and various routes of use for IMFs. Enhanced treatment for substance use disorders is also needed to address the increased risk for overdose (4) and treatment complications (5) associated with using IMFs with stimulants.

MMWR Morb Mortal Wkly Rep 2021;70:1740-1746.

By The Scottish Drug Deaths Taskforce

This, the final report of the Scottish Drug Deaths Taskforce, sets out a suite of evidence-based recommendations and actions that will reduce drug-related deaths and harms and improve and save the lives of people who use drugs. Our final report has four substantive chapters. 1. Context: explores where we are now, gives an overview of the work of the Taskforce to date and discusses the legal context in which Scotland operates. 2. Culture: sets out what the ethos of the system should be and the changes that are needed to achieve this. It calls for broad culture change from stigma, discrimination, politicisation and punishment towards care, compassion and human rights. 3. Care: investigates what is needed to deliver an effective, consistent, personcentred, whole-systems approach that delivers high-quality care. It builds on the principle that drug dependency should receive parity with any other health conditions, with people getting the care they need when they need it. 4. Co-ordination: sets out the foundations of the changes that are required, including targeted resource and decisive leadership. Twenty overarching recommendations are provided at the beginning of the report. Each chapter then includes evidence-based actions that are summarised in a table at the end of the report.

Edinburgh: The Scottish Drug Deaths Taskforce, 2022. 135p.

By Chloe Gilroy

The nexus between illicit drug economies and great power competition is a critical, yet understudied, dimension of counternarcotics. If policy experts and academics understood how great power competition intersects with illicit drug economies, then counternarcotics experts would have yet another incisive theoretical lens through which to understand drug flows. This paper contends that China is unwilling to crack down on chemical precursor flows that feed the Western Hemisphere’s synthetic drug trade due to its broader geopolitical imperatives, which are shaped by great power competition. Chinese pharmaceutical and chemical producers are taking advantage of un-checked drug demand in the United States by selling chemical precursors to Mexican drug trafficking organizations that manufacture and smuggle synthetic drugs across the U.S.-Mexico border. Their involvement in the Western Hemisphere drug trade has expanded the market for synthetic drugs and has destabilized Mexico’s criminal landscape. The Chinese government’s response to the export of massive quantities of illegal drugs and precursor chemicals is largely driven by external pressure and characterized by a lack of credible commitment to reduce the flow of illegal drugs and precursor chemicals. This paper will start by delving into the existing literature on great power competition and illicit drug economies before exploring China’s approach to drug control. It will then dissect trafficking patterns in two synthetic drugs, methamphetamine and fentanyl. After that, it will explain how Beijing’s incentives in the pharmaceutical and chemical sectors impact methamphetamine and fentanyl export volumes. This paper will conclude by comparing time series data on methamphetamine and fentanyl seizures at the U.S.-Mexico border with the progression of China’s enforcement efforts.  

Washington, DC: William J. Perry Center for Hemispheric Defense Studies, 2020. 28p.

By Vanda Felbab-Brown

Synthetic opioids remain the source of the deadliest U.S. drug epidemic ever. Since 1999, drug overdoses have killed approximately 1 million Americans,[1] an overdose lethality that has increased significantly since 2012 when synthetic opioids from China began supplying the U.S. demand for illicit opioids. Even though China placed the entire class of fentanyl-type drugs and two key fentanyl precursors under a controlled regulatory regime in May 2019, it remains the principal (if indirect) source of U.S. fentanyl. Fentanyl scheduling and China’s adoption of stricter mail monitoring has created some deterrence effects. Instead of finished fentanyl being shipped directly to the United States, most smuggling now takes place via Mexico. Mexican criminal groups source fentanyl precursors — and increasingly pre-precursors — from China, and then traffic finished fentanyl from Mexico to the United States. Scheduling of fentanyl and its precursors in China is not sufficient to stem flows to the United States.

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  There is little visibility into China’s enforcement of its fentanyl regulations, but it clearly remains limited. U.S.-China counternarcotics cooperation remains fraught, and from the U.S. perspective inadequate. Rejecting U.S. blame of China for the opioid epidemic and emphasizing U.S. responsibilities for that calamity, Beijing points to its benevolence in anti-drug cooperation. But China’s cooperation with the U.S. in the global counternarcotics campaign has been subordinated to the overall deteriorated geostrategic relationship between the two superpowers. There is little prospect that in the absence of significant warming of the overall U.S.-China bilateral relationship, China would significantly intensify its anti-drug cooperation with the United States. U.S. punitive measures, such as sanctions and drug indictments, are unlikely to change that. Structural characteristics of synthetic drugs, including the ease of developing similar, but not scheduled synthetic drugs and their new precursors — increasingly a wide array of dual-use chemicals — pose immense structural obstacles to controlling supply, irrespective of political will to prohibit and regulate their use and enforce the regulations.

New York: Brennan Center for Justice, 2022. 84p.

By Jason Eligh

The purpose of this report is to examine the existing retail markets for meth across several countries in eastern and southern Africa. This will be achieved through an analysis of meth availability, retail meth prices, distribution systems and domestic marketplaces. The report provides an analytical summary of meth markets that is grounded in data collected in 10 countries across the region with details of specific retail price points, commentary on domestic meth distribution systems and structures, and discussion of common structural characteristics across the region that enable and sustain these markets. Furthermore, the data generated from research undertaken for this report is intended to contribute to the broader regional objective of constructing an open-source database of time-series, country-specific illicit commodity price data, where applicable and practicable.

Geneva: Global Initiative Against Transnational Organized Crime, 2020. 104p.

By Jason Eligh

The implications of the coronavirus pandemic for governance and law enforcement will be profound and, from the perspective of illicit drug markets, the global disruption caused by COVID-19 can be seen as both a crisis and an opportunity. World drug markets have already weathered a number of historical market crises. In each of these situations, illicit drug organizations and their markets suffered significant short-term disruptions to demand or supply, or both. Also, in each of these situations, a majority of the affected organizations and markets adapted and evolved their business models to accommodate the new operating environments. Today, many domestic drug markets are reasonably stable, embedded in their economic landscapes. They are significant components of regional and national gross domestic product and, in many places, a significant or sole livelihood source. Key factors that have shaped drug markets in the past, and continue to shape them today, are exploitation of opportunity amid crisis and rapid adaptation to environmental change.

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  COVID-19 will generate longer-term implications for drug-market dynamics, law-enforcement tactics and drug policy. This policy brief offers observations on the current and likely future drug market impacts of the coronavirus pandemic, with discussion of policy-response measures as we draw closer to the inevitable post-pandemic recovery period of stock taking and reflection.

Geneva: Global Initiative Against Transnational Organized Crime, 2020. 37p.

By Gianmarco Daniele, Marco Le Moglie, Federico Masera

The opioid epidemic and migration along the US–Mexico border are two of the most-debated policy issues in recent US politics. We show how these two topics are interlinked: the US opioid epidemic generated large Mexican migration flows. We exploit the fact that in 2010, a series of reforms to the US health care system resulted in a shift in demand from legal opiates to heroin. This demand shock had considerable effects on Mexico, the main supplier of heroin consumed in the US. Violence and conflicts increased in Mexican municipalities suitable for opium production, as they became highly valuable to drug cartels. People migrated out of these municipalities to escape this violence, mostly to areas close to the US border and into the US. The rise in US demand for heroin increased internal migration by an estimated 90,000 individuals and migration across the border at least by 12,000

BAFFI CAREFIN Centre Research Paper No. 2020-141, 2020. 60p.

By Harvey Slade

Drug-related deaths fell after the reform of Portugal’s drug policy, and have remained below the EU average since 2001 The proportion of the prison population sentenced for drug offences has fallen from over 40% to 15% Rates of drug use have remained consistently below the EU average Portugal has gone from accounting for over 50% of yearly HIV diagnoses linked to injecting drug use in the EU to 1.7%

London: Transform Drug Policy Foundation, 2021. 10p.

By Lucas Marín Llanes and Hernando Zuleta

There is scarce empirical evidence on the impacts of drug consumption decriminalization, especially, on problematic drug use and violence. In 2001, Portugal decriminalized the consumption of all illicit drugs. In this paper, we focus on determining the short, medium, and long-term impact of Portuguese decriminalization on mortality due to drug use and homicides, from both theoretical and empirical perspectives. We model drug consumption using an intertemporal consumption model and the decisions of trafficking firms to gain market share employing an optimization model. Our results suggest a non-linear effect of decriminalization on drug consumption risk and increasing incentives for firms to expand their market share employing violence after decriminalization. Empirically, we estimate a negative short-run effect on drug-related deaths and null long-run impacts of this legal reform. In terms of homicides, we find a positive effect in a range of 28.7%-34.2% in the medium- and long-term.

Colombia: Universidad de los Andes, 2022. 38p.

By Geoff Ramsey and David Smilde

While corruption and organized crime are thriving amid Venezuela’s political and economic crisis, previously unpublished U.S. government drug trade monitoring data suggests that Venezuela is not a primary transit country for U.S.-bound cocaine. In “Beyond the Narcostate Narrative,” the authors assess the implications of official U.S. drug control data for prospects at advancing a peaceful, negotiated return to democracy in Venezuela.  When U.S. policymakers talk about Venezuela’s crisis, the flow of cocaine through the country is a frequent talking point. And there is no question that organized crime and corruption have flourished in the midst of Venezuela’s crisis. Yet the true extent of drug trafficking is often magnified by actors who suggest that a negotiated, democratic solution in Venezuela is impossible. The authors have heard some version of “you can’t negotiate with a narcostate” countless times in recent years.

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  This paper uses the U.S. government’s own best estimates of transnational illegal cocaine shipments to gauge the scale and relative importance of Venezuela’s role as a transit country. In particular, we draw on recent data from the U.S. interagency Consolidated Counterdrug Database (CCDB), a multi-source collection of global illegal drug trafficking events that is gathered from intelligence data such as detection and surveillance, as well as interdiction and law enforcement data. According to the Department of Defense, “The CCDB event-based estimates are the best available authoritative source for estimating known illicit drug flow through the Transit Zone. All the event data contained in the CCDB is deemed to be high confidence (accurate, complete and unbiased in presentation and substance as possible).” We have supplemented CCDB estimates with public statements and presentations made by officials at the Drug Enforcement Administration, Department of Defense, and Department of State regarding drug trafficking trends in the Americas. 

Washington, DC: Washington Office on Latin America, 2020. 20p.

By Walter Kemp, Kristina Amerhauser and Ruggero Scaturro

The Western Balkans is a crossroads for the trafficking of many illicit commodities, and a geographical hub for the smuggling of migrants who are trying to enter Western Europe. While these facts are well known, information on the size of the markets and the potential profits is less evident. And while the Western Balkans has a bad reputation for laundering illicit proceeds, there is not much information on cities or sectors where it is a problem. This report sheds light on the dark numbers of mixed migrant flows through the Western Balkans, the prices that they pay to be smuggled, as well as the cost of drugs in the region. To do this, it uses an approach pioneered in two previous Global Initiative Against Transnational Organized Crime (GI-TOC) reports on organized crime in the Western Balkans, namely pinpointing and looking at what is going on in selected hotspots, especially high-volume entry and exit routes through which migrants are smuggled, and key drug trafficking nodes. Focusing on illicit activity in these hotspots provides a close-up look at the drivers and enablers of organized crime. At the same time, an analysis of these hotspots in a regional context gives an indication of the volume of illicit trade and the potential profits being made.

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  After looking at the amounts of money being made in these hotspots and showing where and how the smuggling of migrants and drugs is taking place, the report looks at a third flow – money. The third section of the report explains how money laundering works in the region both in terms of cleaning small amounts in the informal economy as well as bigger volumes generated by serious organized crime and large-scale corruption. It identifies sectors and industries as well as particular hotpots in the Western Balkans that are particularly vulnerable to money laundering. This report contains a wealth of information that was gathered in the fourth quarter of 2020 – despite the COVID-19 pandemic. The findings are based on field research and interviews carried out with current and former law enforcement officials; investigative journalists; researchers; local officials; asylum seekers and migrants; drug users; humanitarian agencies; international organizations; and representatives of civil society in the hotspots. It also draws on secondary sources, such as analytical and media reports, and official government information. To make this information more user-friendly, a number of maps and graphics have been specially produced for this report.

Geneva: Global Initiative Against Transnational Organized Crime. 2021. 88p.

By The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA)

The Trends and Developments report presents the EMCDDA’s latest analysis of the drug situation in Europe. Focusing on illicit drug use, related harms and drug supply, the report contains a comprehensive set of national data across these themes and key harm-reduction interventions.

Lisbon: EMCDDA, 2022. 60p.

By Anne T. Gallagher and Fiona David

Whether forced into relocation by fear of persecution, civil war, or humanitarian crisis, or pulled toward the prospect of better economic opportunities, more people are on the move than ever before. Opportunities for lawful entry into preferred destinations are decreasing rapidly, creating demand for a range of services that is increasingly being met by migrant smugglers: individuals or criminal groups who facilitate unauthorized entry into in another country for profit. This book, a companion volume to the award-winning The International Law of Human Trafficking, presents the first-ever comprehensive and in-depth analysis of the international law of migrant smuggling. The authors call on their direct experience of working with the United Nations to chart the development of new international laws and to link these specialist rules to other relevant areas of international law, including law of the sea, human rights law, and international refugee law. Through this analysis, the authors identify and explain the major legal obligations of States with respect to migrant smuggling, including those related to criminalization, interdiction and rescue at sea, protection, prevention, detention, and return.

Cambridge, UK: Cambridge University Press, 2014. 840p.

By Jens Beckert and Matías Dewey

From illegal drugs, stolen artwork, and forged trademarks, to fraud in financial markets - the phenomenon of illegality in market exchanges is pervasive. Illegal markets have great economic significance, have relevant social and political consequences, and shape economic and political structures.Despite the importance of illegality in the economy, the field of economic sociology unquestioningly accepts the premise that the institutional structures and exchanges taking place in markets are law-abiding in nature. This volume makes a contribution to changing this. Questions that stand at the centre of the chapters are: What are the interfaces between legal and illegal markets? How do demand and supply in illegal markets interact? What role do criminal organizations play in illegal markets? What is the relationship between illegality and governments? Is illegality a phenomenon central to capitalism? Anchored in economic sociology, this book contributes to the analysis and understanding of market exchanges in conditions of illegality from a perspective that focuses on the social organization of markets. Offering both theoretical reflections and case studies, the chapters assembled in the volume address the consequences of the illegal production, distribution, and consumption of products for the architecture of markets. It also focuses on the underlying causes and the political and social concerns stemming from the infringement of the law.

Oxford, UK: Oxford University Press, 2017. 315p.